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The AMLS hypothesis postulates that in neuroinflammatory infectious diseases, such as TBM, lactate produced through glycolysis in astrocytes participates in the activated immune response and, in association with ketones and gluconeogenic amino acids, is collectively directed from the neurons preferentially into microglia

Thus, we will not describe their other uses in detail further

NF-B: A Neuroprotective Role or a Neurotoxic Role In the CNS, NF-B transcription factors are key players in a number of physiological processes such as neurogenesis (Rolls et al., 2007), and synaptic plasticity which related to learning and memory (ORiordan et al., 2006