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All samples were collected with the patients written informed consent

Diselenide bonds enhance efficacy via ROS generation, while Pt(IV) prodrugs are reduced to active Pt(II) by GSH, overcoming cisplatin limitations

The infrared (IR) spectra were obtained with a Nicolet Nexus-670 FT-IR spectrometer

When to seek further advice Contact your GP or prescribing clinician if you: Experience severe or persistent nausea, vomiting, or abdominal pain Develop symptoms consistent with pancreatitis: severe upper abdominal pain radiating to the back, particularly after eating Notice signs of hypoglycaemia (shakiness, sweating, confusion) if you're also taking insulin or sulfonylureas Are concerned about rapid muscle loss or persistent fatigue during treatment Have purchased or used unlicensed peptide products and are experiencing adverse effects - seek medical advice without delay A full list of known side effects and drug interactions is available in the patient information leaflet supplied with your medication