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Description

Notably, the glutathione S-transferase proteins represent an extended family of multifunctional enzymes that are involved in diverse pathways such as oxidative stress response, and detoxification of various substrates 28

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HK2-OE resulted in a significant decrease in ROS production and apoptosis in HL-1 cardiomyocytes

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This should be considered in individuals with diabetes or those at risk of hypoglycemia

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Such results are consistent with growing evidence that alternate ligands for GPCRs exhibit biased agonism

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