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3.1 The immunoregulatory characteristics of bacterial pneumonia: microbial flora metabolism and immune collaborative defense mechanisms The immune regulation in bacterial pneumonia (e.g., infections caused by Streptococcus pneumoniae and Pseudomonas aeruginosa ) is closely linked to the interaction between gut microbiota and host metabolism

3 Possible mechanisms of atrial fibrillation caused by ferroptosis Activation of the renin-angiotensin-aldosterone system (RAAS), inflammation, oxidative stress, apoptosis, and autonomic imbalance are interconnected factors that contribute to the persistence of AF (Van Wagoner and Chung, 2018)

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Thus A combinatorial strategy would very certainly be required [11]