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When the receptor is engaged, it kicks off intracellular signaling cascades that drive both protein-building activity and cell proliferation

Feb 19:2025.02.17.638647

In the Si-DSS group, the amount of retained hydrogen followed the same pattern as that in the Con-DSS group

Collectively, these results suggested that oxygen-deprived conditions in the COVID-19 lung mediates a metabolic switch from aerobic FAO and OXPHOS towards anaerobic glycolysis in ECs, which is strongly linked to mitochondrial dysfunction