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AKT1 phosphorylates FDX1 at Ser63, a modification that disrupts FDX1s ability to promote lipoylation of DLAT and other TCA cycle enzymes

While various methods of protein quality assessment exist, most of these approaches center upon the amount of EAAs that are found within the protein source, and in nearly all situations, the highest quality protein sources are those containing the highest amounts of EAAs

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Our findings highlight the need for caution in the indiscriminate use of antioxidants, showing that supplementation in healthy males is not harmless and that perturbing the paternal redox balance may alter developmental programming and induce teratogenic outcomes