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doi: 10.1371/journal.ppat.1005972 170 TripathiDRadhakrishnanRKThandiRSPaidipallyPDevalrajuKPNeelaVSKet al

Firstly, PLSCR1 can bind to EGFR and enhance its phosphorylation level, which may interfere with the efficacy of many drugs targeting EGFR (eg: Lapatinib)