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Consistent with the distribution of Firmicutes in the cecal samples, the relative abundance of Ileibacterium was highest in the WD controls (average relative abundance 68%), second highest in the LD controls (average relative abundance 51%), and lowest in the vehicle- and 5A-1MQ-treated mice switched from WD to LD (average relative abundances of 40% and 41%, respectively)

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This analysis gives researchers confidence in their data and supports reproducibility required for publications and peer review

5-Amino-1MQ steps in as an NNMT inhibitor, effectively dialing down this enzymes activity