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They represent approximately 83% of the SCFAs pool within the colon, with their relative distribution remaining stable at 60:25:15, respectively [11]

Li et al (76) found that the percentages of the apoptotic cells for HCT116 cells increased from 4.7-35.2% in the control group and the Polyphyllin II treated group (4 M) and for SW620 cells from 4.6-27.3% in the control group and the Polyphyllin II treated group

However, prolonged high doses (357384 mg/kg over 14 weeks) led to cumulative toxicity (Niho et al., 2001)

Plant extracts as biocontrol agents against Aspergillus carbonarius growth and ochratoxin A production in grapes