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Several novel agents, such as the antisense oligonucleotide pelacarsen and the small interfering RNA therapies of olpasiran, lepodisiran, and zerlasiran, are under investigation and have shown the potential to reduce Lp(a) levels by over 80 % in individuals with markedly elevated Lp(a) concentrations (150 nmol/L) [27]

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military's Central Command shows the fire aboard the bulk carrier True Confidence after a missile attack by Yemen's Houthi rebels in the Gulf of Aden on Wednesday, March 6, 2024