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Furthermore, the study develops a prognostic risk model based on identified glutathione metabolism-related differential genes to evaluate its potential applications in predicting immunotherapy efficacy, determining drug sensitivity, and stratifying prognostic risk

Recent study show that cellular NADPH could be largely generated by PPP, the folate-mediated one-carbon metabolism and ME in cancer and proliferation cells

4.1.3 Hepatocellular inflammation Lipotoxic hepatocyte-derived EVs cause hepatocellular inflammation

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