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Although our collective findings pointed at excess oxidative stress in the cytosol of parkin-deficient brain (herein), these unbiased proteomic screens had previously identified dysregulated cytosolic as well as mitochondrial enzymes without apparent difference in mitochondrial structures (or numbers) within neurons of the nigrostriatal pathway [22, 36]

4.3.2.3 TGF-B signaling blockage TGF-B signaling plays a major part in various biological processes, such as cellular proliferation, differentiation, migration, and cell death

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Global and regional estimates of COPD prevalence: Systematic review and meta-analysis