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Dihexa or its analogs were administered 5 minutes after scopolamine, either intracerebroventricularly at doses of 0.1 or 1 nmol), intraperitoneally at doses of 0.05, 0.25, or 0.50 mg/kg, or orally at doses of 1.25 or 2.0 mg/kg

Anti-inflammatory activity: Researchers report suppression of inflammatory signaling like NF-B, along with reductions in cytokines tied to redness, irritation, and tissue stress

The mice were housed in cages placed in a quiet and temperature-humidity controlled room (22C1-2C) with a 12 hr light-dark cycle

HGF and VEGF play a synergistic effect in promoting endothelial cell survival by enhancing the anti-apoptotic genes Bcl-2 and A1 (Xin et al., 2001)