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Researchers study MOTS-c because it acts like a chemical signal

An important role of GSSG in the NFB activating signal cascade is suggested by the facts that the potent NFB inducer, tetradecanoyl phorbol acetate, increases intracellular GSSG levels and GSSG/GSH ratios3

Efficacy and Safety of Testosterone Treatment in Men: An Evidence Report for a Clinical Practice Guideline by the American College of Physicians

Given that the N-terminus of AtSNX2a harbors a long intrinsically disordered region, only the amino acid sequence corresponding to residues 157587 was used for structure prediction (parameters: protein entity, single copy, 10 replicate predictions)