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Therapeutic Goods Administration, 2022)

10.1007/s10147-020-01832-5 74 TejeroJ.ShivaS.GladwinM

A multicenter phase-1b/2a study is being conducted to evaluate the safety and immunogenicity of this vaccine in Alzheimers disease (AD) patients(NCT04445831).BIIB092 is a humanized monoclonal antibody developed against an N-terminal fragment of tau (extracellular tau) secreted from familiar AD-patient-derived pluripotent stem cells