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2012 Wolff BG, Michelassi F, Gerkin TM et al (2004) Alvimopan, a novel, peripherally acting mu opioid antagonist: results of a multicenter, randomized, double-blind, placebo-controlled, phase III trial of major abdominal surgery and postoperative ileus

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In conclusion, these findings provide important insights for further research into the specific mechanisms of EMPA and MET in the treatment of HFpEF