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D.GangulyK.LimK.-T

Zinc chelators inhibit eotaxin, RANTES, and MCP-1 production in stimulated human airway epithelium and fibroblasts

Use caution/avoid: active hemorrhoids, inflammatory bowel flares, recent GI surgery, pregnancy/breastfeeding, dehydration, uncontrolled anticoagulation/bleeding risk, electrolyte imbalancescreening is required

It promoted TAM polarization toward M1 macrophages, suppressed Treg cell infiltration at tumor sites, and alleviated immune suppression in the tumor microenvironment (265)