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In summary, growing evidence underscores that gut microbiota dysbiosis plays a pivotal role in both the development and outcome of ischemic stroke through immune, barrier, and metabolic pathways, suggesting that restoring gut microbial balance could become an essential strategy for stroke prevention and recovery

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Transcript per million values were shown from cARLA-treated hECs (samples GSM7034228, GSM7034229, GSM7034230 and GSM7034231)

As an effect of Mgd1 and/or Adh1 in terms of me- thylglyoxal oxidation activity, it is suggested as part of the en- zyme catalytic environment needed for methylglyoxal oxida- tion or reduction