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Cortisol, Stress, and Rosacea Flares Many rosacea patients report worsening during periods of: High stress Poor sleep Emotional strain Burnout Chronic stress may increase: Inflammatory cytokines Histamine release Sympathetic nervous system activation Vascular instability This may intensify flushing and skin sensitivity

These properties make it particularly relevant in contexts where oxidative stress drives tissue damage: photoaging, COPD, post-injury inflammation, and metabolic disease

NAD+ is the better first move when the presenting complaint is systemic: fatigue, brain fog, metabolic slowdown, or recovery from chronic stress

Dihexa is another neuro-focused peptide that appears to enhance communication between brain cells