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Lenalidomide, a 4-amino-glutamyl analogue of thalidomide, is used to treat multiple myeloma (MM) [58] and myelodysplastic syndromes (MDS) [59], and also lenvatinib, which acts as a multiple kinase inhibitor against the VEGFR1, VEGFR2, and VEGFR3 kinases, is applied for the treatment of thyroid cancer [60]

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In a study of a mouse unilateral ureteral obstruction (UUO) model, Takahashi et al

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