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Evidence Synthesis Given heterogeneity in models, dosing, and outcome reporting, findings were summarized using structured narrative synthesis rather than quantitative pooling

Cagrilintide vs retatrutide Retatrutide is a triple agonist targeting GIP, GLP-1, and glucagon receptors simultaneously

26 To determine whether TGF 1 is exerting its effects through a SMAD3-dependent mechanism, bEnd.3 cells were treated with rTGF 1 and the SMAD3 antagonist SIS3