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showed that oleoyl-CoA and oleic acid could inhibit HSL activity at 0.1 M and 0.5 M, respectively (126)

This dual mechanism enhances glucosedependent insulin secretion while suppressing glucagon release, slowing gastric emptying, and promoting satiety through central appetite regulation [2]

A number of epidemiologic studies have revealed that insomnia is more common in patients with T2DM than in non-diabetic controls and independently associated with T2DM [1,2,3,4,5]