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Reported reactions included nausea, vomiting, chills, low blood pressure, breathing difficulty and hospitalization, with excessive endotoxin exposure identified as a concern

Influence of time of day of blood pressurelowering treatment on cardiovascular risk in hypertensive patients with type 2 diabetes

Additionally, mtDNA damage has been associated with PD etiology and progression (Tresse et al., 2023) and mitochondrial dysfunction is linked genetically to PD, since many mutations associated to familial cases of PD were found in genes such as PINK1 or PARKIN, which regulate mitochondrial turnover (Valente et al., 2004