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Annals of the New York Academy of Sciences, 1033(1), 3041

Pharmacodynamic Vs Pharmacokinetic Assays for DOAC Measurement Two general types of coagulation assays can be used to assess an anticoagulants presence or activity functional, pharmacodynamic (PD) assays that measure the dynamics of clot formation as its endpoint (Figure 1), and quantitative or pharmacokinetic (PK) assays that measure drug concentration9