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High homocysteine not responding to methylfolate : A 2023 RCT found people with MTHFR C677T had better homocysteine balance with folinic acid than methylfolate. Who Should Avoid Folinic Acid: MTHFS Variants The MTHFS enzyme converts folinic acid into other usable folate forms

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A study on a nickel-catalyzed SOD enzyme showed that it had a solvent KIE of 20 favoring protons over deuterons by a factor of 20