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Could the decrease in the endothelial nitric oxide (NO) production and NO bioavailability be the crucial cause of COVID-19 related deaths

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Medical management includes starting PGE1 to keep the ductus arteriosus open and treatment of metabolic acidosis if present

Figure 6-3 A , C , Relative expression (fold change compared with CON) of selected genes ( A ) and genes related to IGF-1 signaling in the hippocampus on P9 analyzed by qPCR ( C )