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Glutaredoxins can catalyze reduction of DHA in vitro (Wells et al., 1990)

The primary contributors to ROS production reside in the mitochondria, which supply over 90% of cellular ROS ( 2 - ) is generated through reactions catalyzed by complex I, II and III ( 2 O 2 ), which can freely diffuse into the cytosol ( Another important source of ROS in T cells is the family of nicotinamide adenine dinucleotide phosphate (NADPH) oxidases, including NOX2 and DUOX2

Cell Host Microbe 27 , 841848.e3 (2020)

Oral administration of -glutamylcysteine increases intracellular glutathione levels above homeostasis in a randomised human trial pilot study