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Another cohort study showed an association between adequate dietary intake of copper (equal to or above the estimated average requirement) and a reduced risk of all-cause- and cardiovascular disease-related mortality

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Under normal conditions, NNMT activity can consume substantial amounts of both nicotinamide and SAM, particularly in metabolically active tissues or during periods of metabolic stress

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Biomed Pharmacother 110:8594 Dinkova-Kostova AT, Abramov AY (2015) The emerging role of Nrf2 in mitochondrial function

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