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55,56 Its pathogenesis is highly complex, involving the interplay of factors including lipid metabolism disorders, 57 insulin resistance, 10 oxidative stress, 58 immune activation, 13 and gut microbiota dysbiosis

What is the Endothelium

However, rather than directly affecting FAO, SCAP deficiency suppressed regulation of genes involved in sterol biosynthesis, including critical enzymes such as 3-hydroxy-3-methylglutaryl coenzyme A reductase

[2] Choline chloride serves as an essential substrate for phosphatidylcholine and betaine formation, thereby enhancing bile-dependent lipid emulsification and acting as an osmolyte that maintains hepatocyte membrane integrity under oxidative stress