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Interestingly, administration of TVX to 2D cultured LSECs did not result in decreased viability at all TVX concentrations, indicating that the toxicity in the 3D model is primarily due to direct injury of HepaRG cells and subsequently, as a secondary response, damage to LSECs

doi:10.1002/kjm2.12723 499. Santoso B, Rahmawati NY, Saadi A, Dwiningsih SR, Annas JY, Tunjungseto A, Widyanugraha MYA, Mufid AF, Ahsan F

Depletion of microglia attenuates dendritic spine loss and neuronal apoptosis in the acute stage of moderate traumatic brain injury in mice

17 It became clear that these two extracts may work together to: Decrease inflow of aqueous humor