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V c bn c hai l mt hp cht c to thnh t 3 loi acid amin: glutamine, cysteine v glycine

Moreover, as lysosomal function is essential for mitophagy, impairment in the fusion of lysosomes with autophagosomes-containing mitochondria may compromise the clearance of dysfunctional mitochondria, resulting in exacerbated APAP hepatotoxicity

Antioxidants 11(1):87

Malnutrition and Micronutrients Deficiency The onset of ALN is intensified by several risk factors such as malnutrition, thiamine deficiency, direct and indirect toxic effects of alcohol and its metabolites on nerve fibers, and genetic predispositions of patients [55, 139,140,141,142,143]