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Bioinformatics 35 , 41684169 (2019)

Preventing bone diseases Age-related bone disorders like osteoporosis result from an imbalance between osteoclastic and osteoblastic activity

10.1155/2014/761264 42 RatherH

[194] Moreover, uremia, the buildup of waste products in the blood that occurs as a result of declining or decreasing kidney function, can lead to inflammation and reduction in the immune system's ability to function as evidenced by an increased risk of viral-associated cancers, increased susceptibility to infections, and decreased vaccination responses in patients with ESRD