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Seiwerth, R

10.1038/sj.onc.1203245 75 MorrisonA.HodgettsC.GosslerA.Hrab de AngelisM.LewisJ

Q: Why does the body excrete excess riboflavin in urine

Methods Mice To induce genetic ablation of the GHR, mice carrying loxP-flanked Ghr alleles 44 were bred either with AgRP-IRES-Cre mouse (Agrp tm1(cre)Lowl /J, The Jackson Laboratory), LepR-IRES-Cre mouse (B6.129-Lepr tm2(cre)Rck /J, The Jackson Laboratory) or Nestin-Cre mouse (B6.Cg-Tg (Nes-cre)1Kln /J, The Jackson Laboratory)