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The severity of skin inflammation was assessed according to 3 symptoms: erythema, scaling, and thickening

Roles of oxidative stress and inflammation in vascular endothelial dysfunction-related disease

Y.WangZ

The outer and inner mitochondrial membranes are rich in unsaturated fatty acids, and lipid peroxidation products, such as 4-hydroxy-2-nonenal (4-HNE) and malondialdehyde (MDA), alter the fluidity and permeability of the membrane by binding with membrane lipids