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found that AS-IV improved hyperglycemia, insulin resistance, and glucose tolerance in diet-induced and genetically obese mice by elevating circulating levels of adiponectin (Xu et al., 2009)

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The associated risk is modulated by individual factorssuch as BMI, diabetes, dyslipidemia, and genetic backgroundand should be conveyed in a personalized manner

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These data suggest that glutathione depletion, rather than increased ROS generation, has a stronger effect on promoting methylglyoxal sensitivity

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Author Contributions Conceptualization, I.A., A.H., K.M.F.M

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