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Gen Physiol Biophys (2010) 29(1):7984

Biomarker-driven pipelines should include rapid detection of gingival crevicular fluid 4-HNE for patient stratification and monitoring (139)

This suggests that lactylation may promote M2 macrophage polarization, thereby inducing PASMC proliferation and migration, and contributing to the development of PAH [227, 228]