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In 2017, 962 million individuals with CD were 60 years or older, accounting for 13% of the global population (Sanford, 2017)

Waldherr, S

Nature 579 , 507517 (2020)

Many strains of lactic acid-producing bacteria, such as Bifidobacterium and Lactobacillus , are widely used to maintain gut homeostasis and modulate immune responses ( Bifidobacterium and Lactobacillus is significantly reduced ( Bifidobacterium and Lactobacillus are significantly increased ( 2 S, which exacerbates pro-inflammatory responses and impairs intestinal epithelial barrier function ( -Overgrowth of opportunistic pathogens is another characteristic pattern of taxonomic dysbiosis in NIU