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The toxic effect of mSOD1 astrocytes appears specific to motor neurons, as interneurons, GABAergic, and dorsal root ganglia neurons are not affected [31, 32, 36, 38, 39]

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Summary In short: AOD 9604 is a promising fat-metabolism targeted peptide fragment of growth hormone designed to stimulate lipolysis and inhibit lipogenesis, while avoiding many of the typical growth-hormone side-effects

High colocalization of free-GTP with TMRM at young age indicates a major production site in mitochondria, but also associated with old age enlarged cytoplasmic vesicles