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Research has shown that a biallelic poly (AT) insertion/deletion polymorphism in Intron 9 of XPC is associated with increased risk for skin, breast and prostate cancers, [12] [13] [14] especially in North Indian populations

Secreted predominantly by the pineal gland, melatonin coordinates circadian rhythms and peaks during the night in healthy individuals

Such dysfunctional metabolic sequelae are cumulative outcomes of virus-induced HMRD involving about 10 divergent pathophysiological mechanisms, comprising of both virus-derived virulence factors as well as a multitude of extreme innate host responses

Steady-state operation enables regulation of microbial density through removal of unbound microbes, continuous nutrient supply, maintenance of stable pH, and clearance of microbial metabolic wastes, while preserving accurate oxygen gradients