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This chemical library covered 25 pathways in 7 different functional classes in Zmpste24 / MEFs a classic progeroid cell model that shows early cell senescence in vitro [22,23,24] (Fig

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It was concluded that the potency of the compounds in the oxytocinase subfamily is mainly attributed to the occupation of the active site specificity pockets and their orientation in the enzymes (Tsoukalidou et al., 2019)

BPC-157 was the first of seven peptides considered at the July 23-24 meeting