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This neuroendocrine pathway is mechanistically distinct from the hypothalamic and gut-brain circuits predominantly engaged by GLP-1 receptor agonists

BPC-157/TB-500 10+10mg $160.00 Volume discounts Auto-applied at checkout Free shipping on orders of $200+ Compound Identity COMPOUND NAME BPC-157 and TB-500 peptide blend SYNONYMS Body Protection Compound-157 (BPC-157), Thymosin Beta-4 Fragment (TB-500) CAS NUMBER BPC-157: 137525-51-0 TB-500: 77591-33-4 MOLECULAR FORMULA BPC-157: C 62 H 98 N 16 O 22 TB-500: C 212 H 350 N 56 O 78 S MOLECULAR WEIGHT BPC-157: 1419.53552 g/mol TB-500: ~4963.49 g/mol STRUCTURE Synthetic tetrapeptide PEPTIDE SEQUENCE BPC-157: Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val TB-500: Ac-Ser-Asp-Lys-Pro-Asp-Met-Ala-Glu-Ile-Glu-Lys-Phe-Lys-Asp-Lys-Ser-Ile-Lys-Asn-Asp-Lys-Pro-Thr CHEMICAL STRUCTURE BPC-157: TB-500: CHEMICAL STRUCTURE BPC-157: C 62 H 98 N 16 O 22 TB-500: C 212 H 350 N 56 O 78 S Mechanism of Action BPC-157 is believed to act via modulation of nitric oxide pathways, angiogenesis induction, and cytoprotective effects through VEGFR-2 and FAK-paxillin pathways

The cells were sub-cultured, when the cells are 80% confluent, using a cell scraper (AGC Techno Glass Co., Ltd) after processing by DPBS() (no calcium, no magnesium, Thermo Fisher Scientific Inc.) and CTK solution

Cells were treated with vehicle (DMSO) or DMDD for 48 h after incubation with NG or HG DMEM medium for 24 h