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Bifunctional peptidylglcine alpha-amidating enzyme requires two copper atoms for maximum activity

The autophagy-related genes ( Atg5 , Atg12 and Beclin 1 ) were significantly upregulated in the splenic and renal macrophages in activated lymphocytes-derived DNA (ALD-DNA) induced lupus mice and in the peripheral blood mononuclear cells from SLE patients