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Geographical distribution and diversity of gut microbial NADH: ubiquinone oxidoreductase sequence associated with Alzheimer's disease

10.1021/acscentsci.7b00028 105 Zoni-BerissoM.LercariF.CarazzaT.DomenicucciS

However, excessive cholesterol accumulation disrupts this equilibrium and contributes to metabolic disorders, including cardiovascular disease, type 2 diabetes mellitus (T2DM), and MASLD [18]

In white adipose tissue, RES decreases adipogenesis and/or de novo lipogenesis, thereby reducing fat storage, and enhances the browning process, which is associated with increased energy expenditure