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RT-PCR was used to measure the gene expression (mRNA) of MMP1 (a metalloproteinase), MMP2, TIMP1, and TIMP2 (tissue inhibitors of metalloproteinases) in treated HDFa cells

If an ME/CFS patient wishes to incorporate physical activity, it should be closely monitored by a team of specialists as over-exertion has the potential to worsen the symptoms of ME/CFS