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Hyperactive Ras in developmental disorders and cancer

C., Uribe, M., & Mndez-Snchez, N

For instance, TREM2 is a key receptor regulating microglial function and a marker protein of DAM phenotype, and its deficiency impairs the ability of microglia to respond effectively to myelin damage, thereby promoting demyelination and neurodegeneration (Poliani et al., 2015)