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Since the blood-brain barrier prevents many dietary antioxidants from entering the brain, it largely relies on endogenous antioxidants such as copper- and zinc-dependent superoxide dismutase (Cu, Zn SOD1)

A lot simply comes down to dietary and lifestyle changes

According to the Mayo Clinic, Peripheral nerves send messages from your brain and spinal cord to the rest of your body, helping you do things such as sensing that your feet are cold and moving your muscles so that you can walk. Peripheral Neuropathy is common in individuals over the age of 55 and refers to general diseases or malfunctions of the nerves as they try to carry messages from the brain and spinal cord to the rest of the body