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DSIP promotes sleep by interacting with various brain regions that govern sleep, such as the hypothalamus and the brainstem (Kastin & Akerstrom, 2003)

Journal 423 (3), 363374

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This process is accompanied by the break/reform of the coordination bond between Cu 2+ and one of the imidazolyls, leading to the redox reaction of Cu 2+ with electron gain or loss 15,16,23,24