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10.1016/j.biopha.2023.114830 157 WangJ.LiS.GuoY.ZhaoC.ChenY.NingW.et al (2023b)

J., Kyu-Youn, Y., & Shin, W

nucleatum reprogrammed adipocytes through two synergistic mechanisms: (1) metabolic activation via CREB/HSL-mediated lipolysis to provide energy substrates, and (2) paracrine signaling through CCL2 secretion to create a tumor-protective microenvironment

In models of hypertension, BPC-157 showed blood pressure-lowering effects, while in hypotensive states, it supported pressure normalization, suggesting homeostatic regulation rather than unidirectional cardiovascular effects