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Senolytics decrease senescent cells in humans: preliminary report from a clinical trial of dasatinib plus quercetin in individuals with diabetic kidney disease

10.1016/j.compositesb.2022.109707 Summary Keywords nanoencapsulation, surface engineering, biomembranes, phase-change materials, anti-cancer Citation Ye Y-T, Xia H-Y, Li J, Wang S-B, Chen A-Z and Kankala RK (2025) Nanoarchitecting intelligently encapsulated designs for improved cancer therapy

The postoperative perfusion in renal tissue is reduced, and the compensatory blood volume in the kidney is increased, which dilates the entering arterioles and constricts the exiting arterioles, thereby maintaining glomerular filtration, leading to renal medullary ischemia and triggering AKI