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Its also known as Vitamin B1. This vitamin helps the body use carbohydrates for energy

As a result, exogenous melatonin has been proposed as a multitasking molecule capable of retarding several processes related to aging such as circadian rhythm dysregulation, metabolic alterations, inflammation, oxidative stress, and mitochondrial dysfunction

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Curcumin has also been reported to suppress the acetylation of RelA mediated by p300 ( Similarly, curcumin greatly decreased the expression of acetylated CBP/p300 HAT, leading to the inhibition of NF-B binding (Yun et al., 2010)